Gerbali  O. Yu.   (V.I. Vernadsky Crimean Federal University, Medical Academy named after S.I. Georgievsky, Simferopol)
                
            
            
    
        
            
            
                
                    
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                         The aim of the study was to study changes in the content of trace elements selenium, selenium, zinc, copper and iron in the wall of a pathologically altered vein in patients with varicose veins of the lower extremities (VV LV) of clinical classes C4-C6. Results. In patients with VV LV of classes C4-C6, a statistically significant decrease in the content of selenium (p<0.001), zinc (p=0.003) and an increase in the content of copper (p=0.046) was found in the wall of the pathologically altered vein. According to multivariate regression analysis, a lower concentration of selenium in the vein wall is associated with the risk of development and progression of VV LV. 
                        Keywords:varicose disease of the lower extremities, trace elements, optical emission spectrometry with inductively coupled plasma. 
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                         Citation link: Gerbali  O. Y.  Features of the content of some microelements in the wall of a pathologically changed vein in patients with varicose veins of the lower limb of clinical class C4 – C6 // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2022. -№08. -С. 158-163 DOI 10.37882/2223-2966.2022.08.11 | 
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