EXPERIENCE OF LAPAROSCOPIC APPROACH IN SURGICAL TREATMENT OF RENAL CANCER COMPLICATED WITH LEVEL 1-2 INFERIOR VENA CAVA TUMOR THROMBUS

Mirzabekov Musabek Kyamranovich, Shkolnik Mikhail Iosifovich, Bogomolov Oleg Alekseevich, Kneev Aleksey Yurievich, Artemov Maksim Vladimirovich

Mirzabekov Musabek Kyamranovich, Department of Radiology, Surgery and Oncology Postgraduate. A.M. Granov Russian Scientifc Center of Radiology and Surgical Technologies of the Ministry of Health of the Russia (Saint-Petersburg) Shkolnik Mikhail Iosifovich, MD, Department of Interventional Radiology and Operative Surgery chief research fellow; Department of Radiology, Surgery and Oncology professor. A.M. Granov Russian Scientifc Center of Radiology and Surgical Technologies of the Ministry of Health of the Russia (Saint-Petersburg) Bogomolov Oleg Alekseevich, PhD (Medicine), Department of Interventional Radiology and Operative Surgery senior fellow; Department of Radiology, Surgery and Oncology assistant professor. A.M. Granov Russian Scientifc Center of Radiology and Surgical Technologies of the Ministry of Health of the Russia (Saint-Petersburg) Kneev Aleksey Yurievich, PhD (Medicine), oncological urology unit attending physician, Department of Radiology, Surgery and Oncology assistant. A.M. Granov Russian Scientifc Center of Radiology and Surgical Technologies of the Ministry of Health of the Russia (Saint-Petersburg) Artemov Maksim Vladimirovich, PhD (Medicine), Deputy Chief Physician for Radiation Diagnostics, Senior Lecturer of the Department of Radiology Surgery and Oncology. A.M. Granov Russian Scientifc Center of Radiology and Surgical Technologies of the Ministry of Health of the Russia (Saint-Petersburg) Abstract Introduction Renal cell carcinoma (RCC) is a malignancy that affects 2-3% of adult population worldwide and is a leading cause of morbidity among tumors of urinary system [1]. Renal vein and inferior vena cava (IVC) thrombosis complicates RCC in 10-14% of cases. This condition is associated with poor prognosis and challenges during surgical treatment. While the mainstay of treatment for removing the kidney affected with a tumor thrombus is through laparatomic approach [6], it may lead to a high rate of intra- and postoperative complications, prolonged intrahospital stay and longer rehabilitation. Aim The aim of this study - to analyze the advantages of laparoscopic approach over open access in surgical treatment of RCC complicated with 1-2 level IVC thrombus. Materials and methods A systematic literature review conducted using Pubmed/Medline and Elibrary databases from March 1, 2021 to March 1, 2023. We have reviewed the modern scientific literature, including randomized controlled studies and meta-analyses on the topic. Results Numerous studies have demonstrated the benefits of laparoscopic approach over open surgery. Laparoscopic approach, however have several limitations, including technical difficulties managing the IVC, the need in experienced surgeons as well as potentially longer operative time.

Keywords:Renal cell carcinoma, tumor thrombus, laparoscopic thrombectomy.