ANALYSIS OF CARDIAC ARRHYTHMIA IN PATIENTS WITH CARDIORESPIRATORY PATHOLOGY AND THE PRESENCE OF OBSTRUCTIVE SLEEP APNEA (OSA)

Kalashnik Daria Nikolaevna, Filipchenko Elena Miroslavovna, Kovrigina Irina Valerievna

The aim of the study was to investigate the nature of cardiac arrhythmias in patients with chronic obstructive pulmonary disease (COPD) and concomitant coronary heart disease (CHD) in the presence of obstructive sleep apnea (OSA). A total of 132 patients with COPD and coronary heart disease were screened to detect OSA. The study randomized 88 patients with COPD and coronary heart disease and OSA: 62 men and 26 women, with an average age of (63.21±8.46) years. The following cardiac arrhythmias were detected during the study: ventricular and supraventricular extrasystoles, paroxysms of supraventricular tachycardia, paroxysms of atrial fibrillation, atrioventricular block of the first and second degrees, sinoatrial block, and atrial fibrillation. In patients with severe OSA (apnea/hypopnea index > 30), more pronounced cardiac arrhythmias were detected in the form of ventricular extrasystoles, atrial fibrillations, and paroxysms of supraventricular tachycardia. An increase in the number of ventricular extrasystoles was detected even in moderate OSA (p < 0.05). It was found that the apnea/hypopnea index can be affected by changes in blood saturation, the presence of paired supraventricular extrasystole, changes in FEV1/FVC, smoking, and the presence of pulmonary hypertension (p = 0.01).

Keywords:cardiac arrhythmia, coronary heart disease, chronic obstructive pulmonary disease, obstructive sleep apnea