Sinitsyn Mikhail Valerevich (Ph.D., Senior Research Associate, Deputy Chief Medical Officer (for work with patients with HIV / TB co-infection), Moscow Scientific and Clinical Center for TB Control)
Ayusheeva Lydia Bulatovna (Ph.D., head of the dispensary department for patients with HIV / TB co-infection, Moscow Scientific and Clinical Center for TB Control)
Galstyan Armine Sergeevna (candidate of the degree Ph.D., phthisiatrician of the tubercular pulmonary department, Moscow Scientific and Clinical Center for TB Control)
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The article discusses the results of the comparative of treatment effectiveness of HIV-positive patients with tuberculosis (TB/HIV+) and HIV-negative TB patients (TB/HIV–), based on cohort analysis for new pulmonary TB cases, and based on dispensary follow up data of TB/HIV+ and TB/HIV– patients. It was showed a significant effect of HIV infection on the TB treatment effectiveness. Treatment effectiveness of new pulmonary TB patients registered in 2013-2014 in the TB/HIV+ cohort was only 56.0% at 84.2% in TB/HIV– cohort. The effectiveness of chemotherapy for TB relapse in TB/HIV+ cohort were also significantly lower than in TB/HIV– cohort of TB relapses – 47.4% against 68.4%. Evaluation of TB treatment outcomes for MDR-TB patients showed better efficacy of treatment in TB/HIV+ cohort compared with the TB/ HIV– cohort: 56.4% and 52.0% of the successfully rate of treatment.
Keywords:HIV infection, tuberculosis, chemoprevention.
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Citation link:
Sinitsyn M. V., Ayusheeva L. B., Galstyan A. S. The effectiveness of treatment of tuberculosis in patients with HIV infection // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2017. -№03-04. -С. 98-103 |
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