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The use of gas chromatography-mass spectrometry technology for assessing sensitin of polymeric antigenic diagnosticum

Simakova D. I.  (The Federal Government Health Institution «Rostov-on-Don Plague Control Research Institute» of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare)

Pisanov R. V.  (The Federal Government Health Institution «Rostov-on-Don Plague Control Research Institute» of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare)

Zacharov M. V.  (The Federal Government Health Institution «Rostov-on-Don Plague Control Research Institute» of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare)

Larionova L. V.  (The Federal Government Health Institution «Rostov-on-Don Plague Control Research Institute» of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare)

Pavlovich N. V.  (The Federal Government Health Institution «Rostov-on-Don Plague Control Research Institute» of the Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare)

Periodically pseudotuberculosis cases in the different countries of the world define relevance of improvement of laboratory diagnosis of a disease. By authors of this paper it is developed experimental polymeric diagnosticum on the basis of the antigens which are a part of proteins of outer membranes of Y. pseudotuberculosis. During the research of a sensitin by gas chromatography-mass spectrometry technology it is shown that the spectrum of the revealed fatty acids corresponds to the fatty acid profile of Y. pseudotuberculosis described in the literature and is represented by antigens of predominantly protein nature with minimum impurities of LPS.

Keywords:Y. pseudotuberculosis, pseudotuberculosis, gas chromatography-mass spectrometry, sensitin, fatty acids, lipopolysaccharides

 

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Citation link:
Simakova D. I., Pisanov R. V., Zacharov M. V., Larionova L. V., Pavlovich N. V. The use of gas chromatography-mass spectrometry technology for assessing sensitin of polymeric antigenic diagnosticum // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2018. -№08. -С. 67-71
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