NSAID-associated gastropathy: current status, problems, possibilities of prevention of therapeutic treatment

Sabitova Diana Al'bertovna

For decades, attempts have been made around the world to develop international and regional guidelines for the treatment of gastrointestinal complications caused by non-steroidal anti-inflammatory drugs. However, none of them still focuses on the direct mechanisms of taking this group of complications under control, emphasizing the need for unification and development of comprehensive clinical guidelines for practitioners that can be implemented in daily clinical reception. In this paper, recommendations are formulated, which are based on large-scale RCTS, systematic reviews and meta-analyses, which suggests the reliability of proposals for the prevention and treatment of gastrointestinal complications induced by NSAIDs.

Keywords:NSAIDs, gastropathy, clinical recommendations, risk factors, proton pump inhibitors