Evalution of the role of sex hormones in the development of myocardial infarction in postmenopausal women

Beibalaeva A. M., Kudaev M. T., Gadjieva T. A.

The article presents the results of a study of the level of sex hormones (estradiol and progesterone) and blood lipids in women with postmenopausal myocardial infarction and the relationship of these indicators. It was established that postmenopausal women with myocardial infarction have lower concentrations of estradiol and progesterone in comparison with the control group, and there are also changes in the blood lipid spectrum. The levels of estradiol and progesterone are inversely correlated with the concentration of cholesterol, low density lipoproteins and triglycerides. The highest statistically significant correlation was observed between the concentration of estradiol and triglycerides in blood serum (R = - 0.474 p = 0.046). The revealed results confirm the point of view on the protective effect of sex hormones in the development of coronary artery disease.

Keywords:myocardial infarction, estradiol, progesterone, lipids, postmenopause.