Nechaeva Elena Avgustovna (Federal State Budgetary Institution "State Scientific Center of Virology and Biotechnology "Vector" Rospotrebnadzor, Koltsovo, Novosibirsk Region, Russia)
Radaeva Irina Fedorovna (Federal State Budgetary Institution "State Scientific Center of Virology and Biotechnology "Vector" Rospotrebnadzor, Koltsovo, Novosibirsk Region, Russia)
Senkina Tatyana Yurievna (Federal State Budgetary Institution "State Scientific Center of Virology and Biotechnology "Vector" Rospotrebnadzor, Koltsovo, Novosibirsk )
Dumchenko Natalya Borisovna (Federal State Budgetary Institution "State Scientific Center of Virology and Biotechnology "Vector" Rospotrebnadzor, Koltsovo, Novosibirsk Region, Russia)
Lipatova Irina Pavlovna (Federal State Budgetary Institution "State Scientific Center of Virology and Biotechnology "Vector" Rospotrebnadzor, Koltsovo, Novosibirsk Region, Russia)
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VectorVac-PS2 serum-free culture medium was developed for the cultivation of MDCK cells and vaccine strains of the influenza virus to create vaccines. The serum-free nutrient medium VectorVac-PS2, when culturing MDCK cells, has high proliferative activity. The production of vaccine strains of influenza virus in cell culture in the VectorVac-PS2 medium is comparable to the production of these strains in serum-free medium SFM4MegaVir. Nutrient medium VectorVac-PS2 can be used in the production of influenza vaccines.
Keywords:viruses, cells, serum-free culture media, vaccines.
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Citation link:
Nechaeva E. A., Radaeva I. F., Senkina T. Y., Dumchenko N. B., Lipatova I. P. The cultivation of MDCK cell in serum-free culture medium to obtain influenza vaccines // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2020. -№01. -С. 33-37 |
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