Features of antibiotic therapy in the treatment of acute destructive pancreatitis

Yashnov A., Konovalova O., Hanina Y., Yashnova N., Passonen E.

Due to the lack of a unified approach to treatment, acute pancreatitis remains an urgent problem in emergency abdominal surgery. However, there is an increase in the incidence of up to 80 cases per 100,000 population. In the structure of emergency surgical pathology, acute pancreatitis ranks 3rd, behind acute appendicitis and gall bladder pathology, and is up to 10-16%. At the same time, severe destructive forms are registered in 15-30% of patients. The mortality rate for severe pancreatitis is 25-40%. In view of the fact that the analyzed literature does not contain uniform data on adequate antibacterial therapy in patients with acute destructive pancreatitis, we attempted to evaluate the effectiveness of double-changing antibiotics.

Keywords:acute pancreatitis, antibiotic therapy, necrotizing pancreatitis, destructive pancreatitis, antibiotics