The role of macrophages in assessing the effectiveness of immunotherapy of chronic endometritis

Kosykh Ekaterina Vladimirovna, Korotkikh Irina Nikolaevna

The article considers such an important aspect as the violation of immunomorphological changes in the endometrium during the development of chronic endometritis (CE). CE, in turn, is the most common cause of the development of female infertility. Of particular importance in the process of implementing changes in the immune response for this pathology is macrophages, an increase in which in the endometrium of women can characterize the intensity of the inflammatory process in tissues and serve as a prognostically unfavorable factor for normal adhesion and blastocyst implantation. The inclusion of Derinat in the complex therapy of chemotherapy helps to restore the main links of the immune system, creating the prerequisites for the effective implementation of in vitro fertilization (IVF).

Keywords:chronic endometritis, infertility, immunity, immune response, endometrium, macrophages, in vitro fertilization (IVF).