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Somatotropic function of the pituitary gland in patients with osteoarthritis

Totrov Igor N.  (MD, Assistant Professor, The North-Ossetian state medical Academy, Vladikavkaz; Institute of biomedical research of Vladikavkaz scientific center of RAS)

Antoniadi Ilona V.  (The North-Ossetian state medical Academy, Vladikavkaz)

Kupeeva Alina M.  (Junior researcher, Institute of biomedical research of Vladikavkaz scientific center of RAS)

Albegova Zarina A.  (Junior researcher, Institute of biomedical research of Vladikavkaz scientific center of RAS)

Ambalova Sima A.  (MD, Professor, The North-Ossetian state medical Academy, Vladikavkaz; Institute of biomedical research of Vladikavkaz scientific center of RAS)

The problem of osteoarthritis (OA) remains relevant today, it is a chronic disease with primary cartilage damage, subsequent proliferation of bone tissue, leading to joint deformities and impaired function. The content of STH (ng/ml) in the blood serum of 45 patients with OA and 20 individuals of the control group was studied. In the examined OA patients, there was a violation of the somatotropic function of the pituitary gland, which was manifested by an increase in the content of STH in the blood serum at the early stages of the disease with a duration of up to 5 years and functional insufficiency of the joints of the I-II degree. In the future, there is a tendency to decrease the level of the hormone in the blood serum, which causes the severity of the process.

Keywords:osteoarthritis, somatotropic hormone, pituitary, blood serum.

 

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Citation link:
Totrov I. N., Antoniadi I. V., Kupeeva A. M., Albegova Z. A., Ambalova S. A. Somatotropic function of the pituitary gland in patients with osteoarthritis // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2020. -№07. -С. 255-257 DOI 10.37882/2223-2966.2020.07.32
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