COMPARATIVE 5-YEAR EVALUATION OF THE RESULTS OF SURGICAL TREATMENT OF MORBID OBESITY AND COMORBIDITIES USING MODERN MODIFICATIONS OF BILIOPANCREATIC DIVERSION

Bordan Natalia Semenovna, Yashkov Yuriy Ivanovich

Aim: to evaluate the long-term comparative effectiveness of SADI and BPD-DS (biliopancreatic diversion with duodenal switch) biliopancreatic diversion modifications. Materials and Methods: 200 patients with morbid obesity operated on according to the BPD-DS (n=100) and SADI (n=100) methods were included. An assessment was made of early and late postoperative complications, as well as a standard set of clinical, laboratory and instrumental examination methods. Results: %EWL 5 years after surgery was 78.4 and 77.7 in SADI and BPD-DS patients, respectively. 5 years after surgery, 84.4% and 91.4% of patients with type 2 diabetes mellitus, 74.0% and 95.5% of patients with dyslipidemia, 94.7% and 96.7% of patients with obstructive sleep apnea achieved remission in SADI and BPD-DS groups, respectively. Early postoperative complications were less in SADI patients than in BPD-DS group (2% and 9%; p<0.05), as well as late ones (16% and 31%; p<0.05). Conclusions: SADI is safe, and its short and long-term outcomes, including weight loss and remission of comorbidities, are similar to BPD/DS.

Keywords:morbid obesity; type 2 diabetes mellitus (DM2); biliopancreatic diversion; biliopancreatic diversion with duodenal switch (BPD-DS); single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S)