GENOTOXIC AND ANTIOXIDANT PROPERTIES OF MEDICINAL PLANTS ACHILLEA BIEBERSTEINII AND HELICHRYSUM ARENARIUM

Gurbanov Ruslan Гурбанович, Dzhambetova Petimat, Bisultanova Zura

Medicinal plants Achillea biebersteinii and Helichrysum arenarium collected in the mountains of Nozhai-Yurt and Shatoi regions of the Chechen Republic were studied. The work was carried out by two methods: Lux-test and Survival test using luminescent strains of Escherichia coli. Studies were conducted on the subject of genotoxicity/antigenotoxicity, oxidative stress/antioxidant effect and bactericidal effect. Infusions of A.biebersteinii and H.arenarium have bactericidal properties, while certain concentrations can increase the viability of bacteria. A.biebersteinii has antioxidant and antigenotoxic effects, potentially infusions >1 g are genotoxic and capable of inducing oxidative stress. H.arenarium infusions have an antioxidant effect that increases with increasing concentration, is able to have an antigenotoxic effect, and also increase genotoxicity together with dioxidine depending on the concentration.

Keywords:Medicinal plants, Achillea biebersteinii, Helichrysum arenarium, genotoxicity, antioxidant activity, E.coli MG1655 lux biosensor