ANALYSIS OF THE MICROBIOME OF THE CONJUNCTIVAL CAVITY IN PATIENTS WITH DIABETIC MACULAR EDEMA BEFORE AND AFTER SURGICAL TREATMENT

Yakiev Abdulnasir Abdulbasirovich

The purpose of this study is to analyze changes in the microbiome of the conjunctival cavity in patients with diabetic macular edema (DMO) before and after surgery. As part of the study, analytical materials were collected on conjunctival smears from patients before and after surgical treatment of DMO. The results of next-generation sequencing were analyzed, quantitative and qualitative analysis of the microbiome was carried out. The results showed significant changes in the composition of the microbiome after surgery. Several cases of bacterial infections in the postoperative period have been described, their diagnosis and effective treatment. This study highlights the importance of understanding the role of the microbiome in the pathogenesis and treatment of diabetic macular edema. The results can be used to develop new therapeutic strategies aimed at modifying the microbiome of the conjunctival cavity, which opens up new prospects in the treatment of this disease.

Keywords:diabetic macular edema, conjunctival microbiome, next generation sequencing, eye surgery, bacterial profile of conjunctiva