GUT MICROBIOLOGIC PROFILE IN PERSONS WITH PSYCHIATRIC DISORDERS

Bugero Nina Vladimirovna, Ilyina Natalia Anatolyevna, Klinkovsky Alexander Igorevich

В Pskov State Budgetary Institution "Pskov Regional Clinical Center of Psychiatry and Narcology" examined 54 patients with various forms of mental disorders. General clinical and laboratory examination (analysis for dysbiotic disorders of intestinal flora and fecal analysis) was performed in all individuals. Determination of the composition of mutually beneficial existence of intestinal microflora representatives was carried out with the study of such parameters as the index of contagiousness, indicators of floristic significance, index of taxa constancy. In the examined persons against the background of decreasing normoflora constancy indexes included conditionally pathogenic microorganisms: p. Enterococcus (C=57,6 %) and fungi p. Candida (C=55.5 %). It was revealed that in patients with psychiatric disorders the number of dominant and floristically significant representatives of symbiotic microflora decreases with an increase in the number of representatives of transit microorganisms, this contributes to changes in the structure of the intestinal cenotype, as a result of the change of dominant species and the distribution of representatives of opportunistic microflora.

Keywords:contagiousness index, floristic significance, compositional constancy index, mental disorders, dominant species, enterococci, Candida fungi