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GIANT JUVENILE BREAST FIBROADENOMA: CLINICAL CASE AND LITERATURE REVIEW

Akhmedov Ruslan Merzialievich  (Oncologist, Pirogov Clinic of High Medical Technologies, St. Petersburg State University (St. Petersburg, Russia))

Bit-Sava Elena Mikhailovna  (Doctor of Medical Sciences, Professor of the Department of Oncology, Pediatric Oncology and Radiation Therapy of the Ministry of Health of the Russian Federation, Head of the Department of Breast Cancer Oncologist (Surgical Methods of Treatment) of the St. Petersburg Clinical Scientific and Practical Center for Specialized Medical Care (Oncological) named after N.P. Napalkov (St. PetersburgSt. Petersburg, Russia))

Ivanov Dmitry Olegovich  (Doctor of Medical Sciences, Professor, Chief Neonatologist of the Ministry of Health of the Russian Federation, Rector of the Federal State Budgetary Educational Institution of Higher Medical Education of the Ministry of Health of the Russian Federation (Saint Petersburg, Russia))

Belousov Alexander Mikhailovich  (MD, Deputy Chief Physician for Medical Affairs (Surgery and Oncology), Pirogov Clinic of High Medical Technologies, St. Petersburg State University (St. Petersburg, Russia))

Fibroadenomas are the most common breast tumors in children and adolescents, accounting for between 30 and 70% of all palpable tumors in patients of this age group, according to various data. Giant juvenile fibroadenoma is a rare benign neoplasm of the breast, most often diagnosed in girls aged 10 to 18 years. Unlike conventional fibroadenomas, which are small in size and characterized by slow growth, giant fibroadenomas are characterized by a rapid significant increase in volume, often reaching a size of more than 5 cm and replacing up to 80% of the volume of the breast. Often, the development of this disease occurs due to dishormonal disorders against the background of puberty. The diagnosis of giant juvenile fibroadenoma and the determination of therapeutic tactics necessarily requires a trepanation biopsy, since they are difficult to distinguish from other neoplasms, such as phylloid tumors, during physical and instrumental examinations. To date, a small number of cases of treatment of these diseases have been described in Russian and foreign literature. The article presents a literature review of current data on the pathogenesis, diagnosis and treatment of giant juvenile fibroadenoma, as well as describes a clinical case of successful surgical treatment of this disease in a 14-year-old patient.

Keywords:fibroadenoma; giant juvenile fibroadenoma; breast tumors; children; adolescents; diagnosis; treatment; trepanation biopsy; dishormonal disorders; surgical treatment.

 

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Citation link:
Akhmedov R. M., Bit-Sava E. M., Ivanov D. O., Belousov A. M. GIANT JUVENILE BREAST FIBROADENOMA: CLINICAL CASE AND LITERATURE REVIEW // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№10. -С. 213-218 DOI 10.37882/2223-2966.2025.10.03
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